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M/S.PURUHOOTHIKA SOFTCONDUCTOR SERVICES HEVS INDUSTRIES.
CANCER DRUGS & VACCINATIONS DISCOVERY & DEVELOPING
BY USING ARTIFICIAL INTELLIGENCE & QUANTUM COMPUTING.
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TOPOISOMERASE ENZYMES ON DNA:
PODOPHYLLOTOXINS:
Etoposide and Teniposide are Potent AntiCancer agents which are used Clinically for a variety of conditions such as Testicular
Cancer
and small Cell Lung Cancer. They are Semi Synthetic Derivatives of "EPIPODOPHYLLOTOXINS" an isomer of a Naturally
Occuring agent
called "PODOPHYLLOTOXIN" where the substituent at position 4 has the opposite configuration.
CAMPTOTHECINS:
CAMPTOTHECINS is a Naturally occuring Cytotoxic alkaloid which was Extracted from a Chinese Bush(Camptotheca Acuminata) in 1966.
It Trgets
the Enzyme "TOPOISOMERASE 1". This Enzyme is similar to "TOPOISOMERASE II" in that it relieves the
Torsional stress of supercoiled DNA
during replication, Transcription and Repair of DNA.
The difference is that it Cleaves only one strand of DNA, whereas
"TOPOISOMERASE II" Cleaves both strands. |